To win the title, the Briton needs to negate a 12-point deficit to teammate Nico Rosberg at Yas Marina - but for Rosberg, a ninth consecutive podium finish will be enough to render Hamilton's task mathematically impossible.
Despite the points situation, Hamilton was keen to look for positives after Sunday’s race at Interlagos, where he took a dominant ninth win of the season.
“I’m happy that I beat everyone today,” he said. “I’m happy that with the same car I beat Nico, and Nico’s driving at his best right now, and today he had nothing on me.
"I’m happy that we as a team are continuing to make history. I’m happy that my new mechanics that I was given at the beginning of the year have gelled so well with me, and now have been doing a fantastic job, I’m happy with that relationship.
"I’m super happy with my engineers, who are the best."
The Briton did, however, concede that him overhauling Rosberg in Abu Dhabi was "unlikely".
“Nico’s doing all he has to do, he’s finished every race, not had any problems, whereas I have," said Hamilton.
"I’m in an awkward position going into the last race. It doesn’t really make a big difference if I go and drive like I do right now, because I’ve already lost so much through the year.
"I can’t give up, because you never know what will happen. It’s unlikely, but you never know what will happen.”
Asked if he would take pride in taking a 10th win of the season in Abu Dhabi, even if the championship ultimately slipped away, Hamilton said: “I am and I will be proud of myself, as long as I continue to perform as I am. And I’m proud of everyone who’s been a part of helping us win all these races.
"What a year, to have nine wins is amazing, and it’s my 31st win with the team, which is crazy. I’m just really, really thankful, these guys have given me such a great opportunity, and the majority of the time I’ve capitalised it.”
Meanwhile, Rosberg laughed off suggestions that his “one race at a time” approach won’t apply for the title showdown.
“I don’t know how I shall approach my last race yet,” said the German. “I shall let you know on Thursday, when I have had a bit more time to think about it.”
Asked if getting through a tricky race in Brazil was the last major hurdle, he said: “Abu Dhabi is going to be a difficult race weekend, like always. It’s always a challenge to do a good job on a race weekend.
"Nothing in F1 is easy. I don’t see it like that.”